林郁茲

專任助理教授【藥理學組】

 

 

TEL: 037-728855 EXT:7125

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 學歷

中國醫藥大學藥學系 藥學學士

中國醫藥大學中國藥學所藥理組 藥學碩士

中國醫藥大學中國藥學所藥理組 藥學博士

實務及教學經歷

中國醫藥學院藥理學實驗 助教

國科會博士班研究計劃 研究助理

台中護校生物學 兼任教師

林志鴻小兒科診所 藥師

正豐生技股份有限公司 研究員

仁德醫護管理專科學校 助理教授

專業證照

藥師執照

校內外服務

校內

護理科教師評議委員

校級教師評議委員

學術研究發展委員

護理科課程圖儀發展委員

護理科福利康樂促進委員

護理科教師成長委員

護理科教學品管委員

教務會議教師代表

研究成果

學位論文

碩士論文:藜蘆鹼及芍藥對於離體大鼠心房相互作用機轉之研究

博士論文:芍藥與藜蘆鹼對於中樞及周邊神經系統相互作用之研究

期刊論文

Lin, Y. T., Chen, Y. F., Tsai, H. Y., Hsieh, M. T. & Chen, C. F. (1996). Effects of veratrine on isolated rat atria. The Chinese Pharmaceutical Journal, 48, 427-439.

Tsai, H. Y., Lin, Y. T., Chen, Y. F., & Chen, C. F. (1997). Effects of veratrine and paeoniflorin in mice by writhing response test. China Medical College Journal, 6, 221-226.

Tsai, H. Y., Lin, Y. T., Chen, Y. F., & Chen, C. F. (1997). The interactions of paeoniflorin and veratrine on isolated rat atria. Journal of Ethnopharmacology, 57, 169-176. (SCI)

Tsai, H. Y., Lin, Y. T., Hsieh, W. T., Lee, C. C., & Chen, Y. F. (1998). Studies of paeoniflorin on induced arrhythmia in the isolated rat atria. China Medical College Journal, 7, 131-136.

Tsai, H. Y., Lin, Y. T., Chen, C. F., Tsai, C. H., & Chen, Y. F. (1999). Effects of veratrine and paeoniflorin on the isolated rat aorta. Journal of Ethnopharmacology, 66, 249-255. (SCI)

Tsai, H. Y., Lin, Y. T., Chen, C. F., Tsai, C. H., & Chen, Y. F. (2001) Effects of paeoniflorin on the formalin-induced nociceptive behaviour in mice. Journal of Ethnopharmacology, 75, 267-271. (SCI)

Tsai, H. Y., Lin, Y. T., Tan, T. W., & Chen, Y. C. (2001) The interaction between paeoniflorin and veratrine on the isolated uterus of rats. The Chinese Pharmaceutical Journal, 53, 137-146.

Chen, Y. C., Lin, Y. T., Tan, T. W., & Tsai, H. Y. (2002). Effects of veratrine and paeoniflorin on isolated mouse vas deferens. Phytomedicine, 9. 296-301. (SCI)

Chen, Y. C., Lin, Y. T., & Tsai, H. Y. (2006). Effects of paeoniflorin on monoamine levels in mice and rat brain using HPLC-microdialysis. Acta Pharmacologica Sinica, 27 (supplement 1), 339. (SCI)

Wu, C. C., Lin, J. P., Yang, J. S., Chou, S. T., Chen, S. C., Lin, Y.T., Lin, H. L., & Chung, J, G. (2006). Capsacin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VHG Cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 601.71-82. (SCI)

Tan, T. W., Tsai H. R., Lu H. F., Lin H. L., Tsou M. F., Lin Y. T., Tsai H. Y., Chen Y. F., & Chung J. G. (2006). Curcumin-induced cell cycle arrest and apoptosis in human acute promyelocytic leukemia HL-60 cells via MMP changes and caspase-3 activation. Anticancer Research, 26: 4361-4372. (SCI)

Yu, F. S., Yang, J. Y., Lin, H. J., Yu, C. S., Tan, T. W., Lin, Y. T., Lin, C. C., Lu, H. F., & Chung, J. G. (2007). Berberine inhibits WEHI-3 leukemia cells in vivo. In Vivo 21: 407-412. (SCI)

LU, H. F., YANG, J. S., LIN, Y. T., TAN, T. W., IP, S. W., LI, Y. C., TSOU, M. F., CHUNG, J. G. (2007). Diallyl Disulfide Induced Signal Transducer and Activator of Transcription 1 Expression in Human Colon Cancer Colo 205 Cells using Differential Display RT-PCR. Cancer Genomics & Proteomics 4 (2): 93-98. (SCI)

YUH-TZY LIN, JAI-SING YANG, HUI-JU LIN, TZU-WEI TAN, NOU-ING TANG, YUNG-HSIEN CHANG, HSU-FENG LU and JING-GUNG CHUNG. (2007) Baicalein Inhduces Apoptosis in SCC-4 Human Tongue Cancer Cells via a Ca2+- -dependent Mitochondrial Pathway. In vivo 21: 1053-1058. (SCI)

YUH-TZY LIN, JAI-SING YANG, SHUW-YUAN LIN, TZU-WEI TAN, CHIN-CHIN HO, TE-CHUN HSIA, TSAN-HUNG CHIU, CHUN-SHU YU, HSU-FENG LU, YUEH-SHAN WENG and JING-GUNG CHUNG. (2008) Diallyl Disulfide(DADs) Induces Apoptosis in Human Cervical Cancer Ca SKi Cells via Reactive Oxygen Species and Ca2+- dependent Mitochondria-dependent Pathway. ANTICANCER RESEARCH 28:2791-2800. (SCI)

Tzu-Wei Tan, Wei-Hung Yang, Yuh-Tzy Lin, Sheng-Feng Hsu, Te-Mao Li, Shung-Te Kao, Wen-Chi Chen, Yi-Chin Fong and Chih-Hsin Tang (2009) Cyr61 increases migration and MMP-13 expression via avb3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells. Carcinogenesis 30(2): 258–268.

Tzu-Wei Tan, Yuh-Tzy Lin , Jai-Sing Yang, Chi-Cheng Lu, Jo-Hua Chiang, Chang-Lin Wu, Jing-Pin Lin, Nou-Ying Tang, hin-Chung Yeh, Ming-Jen Fan and Jing-Gung Chung (2009) A. cantoniensis Inhibits the Proliferation of Murine Leukemia WEHI-3 Cells In Vivo and Promotes Immunoresponses In Vivo. In Vivo 23: 561-566.

Chin-Chung Lin, Jin-Tang Chen, Jai-Sing Yang, Hsu-Feng Lu, Shu-Chun Hsu, Tzu-Wei Tan, Yuh-Tzy Lin, Yi-Shih Ma, Siu-Wan Ip, Jia-Jiuan Wu, Yu-Chinh Li, Jing-Gung Chung (2009) Danthron inhibits the migration and invasion of human brain glioblastoma multiforme cells through the inhibition of mRNA expression of focal adhesion kinase, Rho kinases-1 and metalloproteinase-9. Oncology Reports 22(5): 1033-1037.

Tang CH, Yamamoto A, Lin YT, Fong YC, Tan TW (2010) Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis. Biochem Pharmacol.79(2):209-217.

會議及研討會論文

Tsai, H. Y., Lin, Y. T., & Chen, Y.F. (1999, October). . Studies on the interactions between paeoniflorin and veratrine on the isolated rat uterus.第八屆中華民國基礎神經科學學會年會壁報發表,台中榮總,台中。.

Tsai, H. Y., Lin, Y. T., & Chen, Y.F. (1999, April). Effects of veratrine and paeoniflorin on the isolated rat aorta. Poster session at the The Thirteenth Joint Annual Conference of Biomedical Science,National Yang-Ming University, Taipei, ROC.

Tsai, H. Y., Lin, Y. T., Chien, C.C., Tsai C. H., & Chen, Y. F. (2004, July). The antinociception of paeoniflorin might be via the activation of opioidergic and monoaminergic  system in CNS. Poster session presented at the International Narcotics Research Conference  INRC2004/ Kyoto, Kyoto, Japan.

Tsai, H.Y., Lin, Y.T., Chien, K. W., & Chen, Y. F. (2005, July). Effects of paeoniflorin on neurotoxin-induced neuronal cell damage and experimental parkinsonism in mu-knockout mice. Poster session presented at the International Narcotics Research Conference (INRC), Marriott and Historic Inns, Annpolis, Maryland USA.

Chen, Y. C., Lin, Y. T., & Tsai, H. Y. (2006). Effects of paeoniflorin on monoamine levels in mice and rat brain using HPLC-microdialysis. Poster session presented at the15th World Congress of Pharmacology July 2-7, 2006 Beijing, China.

任教科目

藥理學

進階藥理學

社區健康服務學習

研究計畫

1997~1998  芍藥苷與藜蘆鹼鎮痛相互作用機轉之研究 國科會NSC87-2314-B-039-027

1998~1999  芍藥苷與藜蘆鹼鎮痛相互作用機轉之研究 國科會NSC88-2314-B-039-007

2008/8/1~2009/7/31  Diallyl Disulfide (DADS) Induces Apoptosis in Human Cervical Cancer Ca Ski Cells via Reactive Oxygen Species and Ca2+-dependent Mitochondria-dependent Pathway  校內獎助專題研究計畫

2009/1/1~2009/12/31  CCL5/CCR5 axis promotes the motility of human oral cancer cells.  校內獎助專題研究計畫

 

 

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