林郁茲

職稱：專任助理教授【藥理學組】

姓名：林郁茲　  

電話：037-728855

分機：7125

電子信箱：ytlin58@yahoo.com.tw / liu61yuhtzy@gmail.com

學歷:

中國醫藥大學藥學系 藥學學士 

中國醫藥大學中國藥學所藥理組 藥學碩士

中國醫藥大學中國藥學所藥理組 藥學博士

實務及教學經歷：

中國醫藥學院藥理學實驗 助教

國科會博士班研究計劃 研究助理

台中護校生物學 兼任教師

林志鴻小兒科診所 藥師

正豐生技股份有限公司 研究員

仁德醫護管理專科學校 助理教授

專業證照:

  1. 藥師執照

校內外服務:

(1)校內

  1. 護理科教師評議委員
  2. 校級教師評議委員
  3. 學術研究發展委員
  4. 護理科課程圖儀發展委員
  5. 護理科福利康樂促進委員
  6. 護理科教師成長委員
  7. 護理科教學品管委員
  8. 教務會議教師代表

研究成果:

(1)學術論文

  1. 碩士論文：藜蘆鹼及芍藥對於離體大鼠心房相互作用機轉之研究
  2. 博士論文：芍藥與藜蘆鹼對於中樞及周邊神經系統相互作用之研究

(2)期刊論文

  1. Lin, Y. T., Chen, Y. F., Tsai, H. Y., Hsieh, M. T. & Chen, C. F. (1996). Effects of veratrine on isolated rat atria. The Chinese Pharmaceutical Journal, 48, 427-439.
  2. Tsai, H. Y., Lin, Y. T., Chen, Y. F., & Chen, C. F. (1997). Effects of veratrine and paeoniflorin in mice by writhing response test. China Medical College Journal, 6, 221-226.
  3. Tsai, H. Y., Lin, Y. T., Chen, Y. F., & Chen, C. F. (1997). The interactions of paeoniflorin and veratrine on isolated rat atria. Journal of Ethnopharmacology, 57, 169-176. (SCI)
  4. Tsai, H. Y., Lin, Y. T., Hsieh, W. T., Lee, C. C., & Chen, Y. F. (1998). Studies of paeoniflorin on induced arrhythmia in the isolated rat atria. China Medical College Journal, 7, 131-136.
  5. Tsai, H. Y., Lin, Y. T., Chen, C. F., Tsai, C. H., & Chen, Y. F. (1999). Effects of veratrine and paeoniflorin on the isolated rat aorta. Journal of Ethnopharmacology, 66, 249-255. (SCI)
  6. Tsai, H. Y., Lin, Y. T., Chen, C. F., Tsai, C. H., & Chen, Y. F. (2001) Effects of paeoniflorin on the formalin-induced nociceptive behaviour in mice. Journal of Ethnopharmacology, 75, 267-271. (SCI)
  7. Tsai, H. Y., Lin, Y. T., Tan, T. W., & Chen, Y. C. (2001) The interaction between paeoniflorin and veratrine on the isolated uterus of rats. The Chinese Pharmaceutical Journal, 53, 137-146.
  8. Chen, Y. C., Lin, Y. T., Tan, T. W., & Tsai, H. Y. (2002). Effects of veratrine and paeoniflorin on isolated mouse vas deferens. Phytomedicine, 9. 296-301. (SCI)
  9. Chen, Y. C., Lin, Y. T., & Tsai, H. Y. (2006). Effects of paeoniflorin on monoamine levels in mice and rat brain using HPLC-microdialysis. Acta Pharmacologica Sinica, 27 (supplement 1), 339. (SCI)
  10. Wu, C. C., Lin, J. P., Yang, J. S., Chou, S. T., Chen, S. C., Lin, Y.T., Lin, H. L., & Chung, J, G. (2006). Capsacin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VHG Cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation. Mutation Research – Fundamental and Molecular Mechanisms of Mutagenesis, 601.71-82. (SCI)
  11. Tan, T. W., Tsai H. R., Lu H. F., Lin H. L., Tsou M. F., Lin Y. T., Tsai H. Y., Chen Y. F., & Chung J. G. (2006). Curcumin-induced cell cycle arrest and apoptosis in human acute promyelocytic leukemia HL-60 cells via MMP changes and caspase-3 activation. Anticancer Research, 26: 4361-4372. (SCI)
  12. Yu, F. S., Yang, J. Y., Lin, H. J., Yu, C. S., Tan, T. W., Lin, Y. T., Lin, C. C., Lu, H. F., & Chung, J. G. (2007). Berberine inhibits WEHI-3 leukemia cells in vivo. In Vivo 21: 407-412. (SCI)
  13. LU, H. F., YANG, J. S., LIN, Y. T., TAN, T. W., IP, S. W., LI, Y. C., TSOU, M. F., CHUNG, J. G. (2007). Diallyl Disulfide Induced Signal Transducer and Activator of Transcription 1 Expression in Human Colon Cancer Colo 205 Cells using Differential Display RT-PCR. Cancer Genomics & Proteomics 4 (2): 93-98. (SCI)
  14. YUH-TZY LIN, JAI-SING YANG, HUI-JU LIN, TZU-WEI TAN, NOU-ING TANG, YUNG-HSIEN CHANG, HSU-FENG LU and JING-GUNG CHUNG. (2007) Baicalein Inhduces Apoptosis in SCC-4 Human Tongue Cancer Cells via a Ca2+– -dependent Mitochondrial Pathway. In vivo 21: 1053-1058. (SCI)
  15. YUH-TZY LIN, JAI-SING YANG, SHUW-YUAN LIN, TZU-WEI TAN, CHIN-CHIN HO, TE-CHUN HSIA, TSAN-HUNG CHIU, CHUN-SHU YU, HSU-FENG LU, YUEH-SHAN WENG and JING-GUNG CHUNG. (2008) Diallyl Disulfide(DADs) Induces Apoptosis in Human Cervical Cancer Ca SKi Cells via Reactive Oxygen Species and Ca2+– dependent Mitochondria-dependent Pathway. ANTICANCER RESEARCH 28:2791-2800. (SCI)
  16. Tzu-Wei Tan, Wei-Hung Yang, Yuh-Tzy Lin, Sheng-Feng Hsu, Te-Mao Li, Shung-Te Kao, Wen-Chi Chen, Yi-Chin Fong and Chih-Hsin Tang (2009) Cyr61 increases migration and MMP-13 expression via avb3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells. Carcinogenesis 30(2): 258–268.
  17. Tzu-Wei Tan, Yuh-Tzy Lin , Jai-Sing Yang, Chi-Cheng Lu, Jo-Hua Chiang, Chang-Lin Wu, Jing-Pin Lin, Nou-Ying Tang, hin-Chung Yeh, Ming-Jen Fan and Jing-Gung Chung (2009) A. cantoniensis Inhibits the Proliferation of Murine Leukemia WEHI-3 Cells In Vivo and Promotes Immunoresponses In Vivo. In Vivo 23: 561-566.
  18. Chin-Chung Lin, Jin-Tang Chen, Jai-Sing Yang, Hsu-Feng Lu, Shu-Chun Hsu, Tzu-Wei Tan, Yuh-Tzy Lin, Yi-Shih Ma, Siu-Wan Ip, Jia-Jiuan Wu, Yu-Chinh Li, Jing-Gung Chung (2009) Danthron inhibits the migration and invasion of human brain glioblastoma multiforme cells through the inhibition of mRNA expression of focal adhesion kinase, Rho kinases-1 and metalloproteinase-9. Oncology Reports 22(5): 1033-1037.
  19. Tang CH, Yamamoto A, Lin YT, Fong YC, Tan TW (2010) Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis. Biochem Pharmacol.79(2):209-217.

(3)會議及研討會論文

  1. Tsai, H. Y., Lin, Y. T., & Chen, Y.F. (1999, October). . Studies on the interactions between paeoniflorin and veratrine on the isolated rat uterus.第八屆中華民國基礎神經科學學會年會壁報發表，台中榮總，台中。.
  2. Tsai, H. Y., Lin, Y. T., & Chen, Y.F. (1999, April). Effects of veratrine and paeoniflorin on the isolated rat aorta. Poster session at the The Thirteenth Joint Annual Conference of Biomedical Science，National Yang-Ming University, Taipei, ROC.
  3. Tsai, H. Y., Lin, Y. T., Chien, C.C., Tsai C. H., & Chen, Y. F. (2004, July). The antinociception of paeoniflorin might be via the activation of opioidergic and monoaminergic  system in CNS. Poster session presented at the International Narcotics Research Conference  INRC2004/ Kyoto, Kyoto, Japan.
  4. Tsai, H.Y., Lin, Y.T., Chien, K. W., & Chen, Y. F. (2005, July). Effects of paeoniflorin on neurotoxin-induced neuronal cell damage and experimental parkinsonism in mu-knockout mice. Poster session presented at the International Narcotics Research Conference (INRC), Marriott and Historic Inns, Annpolis, Maryland USA.
  5. Chen, Y. C., Lin, Y. T., & Tsai, H. Y. (2006). Effects of paeoniflorin on monoamine levels in mice and rat brain using HPLC-microdialysis. Poster session presented at the15th World Congress of Pharmacology July 2-7, 2006 Beijing, China.

任教科目:

  1. 藥理學
  2. 進階藥理學
  3. 社區健康服務學習

研究及專案計畫:

  1. 1997~1998  芍藥苷與藜蘆鹼鎮痛相互作用機轉之研究 國科會NSC87-2314-B-039-027
  2. 1998~1999  芍藥苷與藜蘆鹼鎮痛相互作用機轉之研究 國科會NSC88-2314-B-039-007
  3. 2008/8/1~2009/7/31  Diallyl Disulfide (DADS) Induces Apoptosis in Human Cervical Cancer Ca Ski Cells via Reactive Oxygen Species and Ca2+-dependent Mitochondria-dependent Pathway  校內獎助專題研究計畫
  4. 2009/1/1~2009/12/31  CCL5/CCR5 axis promotes the motility of human oral cancer cells.  校內獎助專題研究計畫